Ancestral Health

Beef Liver: Nature's Perfect Food

Beef liver is often called the superfood of the animal kingdom, and is one of the most nutrient dense foods on Earth.

References

  1. Beef, variety meats and by-products, liver, raw Nutrition Facts & Calories [Online]. SELFNutritionData: know what you eat. Available: http://nutritiondata.self.com/facts/beef-products/3468/2
  2. >Staggs, C. G., Sealey, W. M., Mccabe, B. J., Teague, A. M. & Mock, D. M. 2004. Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding. J Food Compost Anal, 17, 767-776.
  3. Kumar, N., Boes, C. J. & Samuels, M. A. 2006. Liver therapy in anemia: a motion picture by William P. Murphy. Blood, 107, 4970.
  4. Sinclair, L. 2008. Recognizing, treating and understanding pernicious anaemia. J R Soc Med, 101, 262-4.
  5. Jacobs, D. R., Jr., Gross, M. D. & Tapsell, L. C. 2009. Food synergy: an operational concept for understanding nutrition. Am J Clin Nutr, 89, 1543S-1548S.
  6. Price, W. A. 1939. Nutrition and physical degeneration; a comparison of primitive and modern diets and their effects, New York, London,, P.B. Hoeber.
  7. Calton, J. B. 2010. Prevalence of micronutrient deficiency in popular diet plans. J Int Soc Sports Nutr, 7, 24.
  8. Ward, E. 2014. Addressing nutritional gaps with multivitamin and mineral supplements. Nutr J, 13, 72.
  9. Hanson, M. A., Bardsley, A., De-Regil, L. M., Moore, S. E., Oken, E., Poston, L., Ma, R. C., Mcauliffe, F. M., Maleta, K., Purandare, C. N., Yajnik, C. S., Rushwan, H. & Morris, J. L. 2015. The International Federation of Gynecology and Obstetrics (FIGO) recommendations on adolescent, preconception, and maternal nutrition: "Think Nutrition First". Int J Gynaecol Obstet, 131 Suppl 4, S213-53.
  10. Calton, J. B. 2010. Prevalence of micronutrient deficiency in popular diet plans. J Int Soc Sports Nutr, 7, 24.
  11. Troesch, B., Biesalski, H. K., Bos, R., Buskens, E., Calder, P. C., Saris, W. H., Spieldenner, J., Verkade, H. J., Weber, P. & Eggersdorfer, M. 2015. Increased Intake of Foods with High Nutrient Density Can Help to Break the Intergenerational Cycle of Malnutrition and Obesity. Nutrients, 7, 6016-37.
  12. Gernand, A. D., Schulze, K. J., Stewart, C. P., West, K. P., Jr. & Christian, P. 2016. Micronutrient deficiencies in pregnancy worldwide: health effects and prevention. Nat Rev Endocrinol, 12, 274-89.
  13. Bird, J. K., Murphy, R. A., Ciappio, E. D. & Mcburney, M. I. 2017. Risk of Deficiency in Multiple Concurrent Micronutrients in Children and Adults in the United States. Nutrients, 9.
  14. Enser, M., Hallett, K. G., Hewett, B., Fursey, G. A., Wood, J. D. & Harrington, G. 1998. The polyunsaturated fatty acid composition of beef and lamb liver. Meat Sci, 49, 321-7.
  15. Byelashov, O. A., Sinclair, A. J. & Kaur, G. 2015. Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid. Lipid Technol, 27, 79-82.
  16. Calton, J. B. 2010. Prevalence of micronutrient deficiency in popular diet plans. J Int Soc Sports Nutr, 7, 24.
  17. Troesch, B., Biesalski, H. K., Bos, R., Buskens, E., Calder, P. C., Saris, W. H., Spieldenner, J., Verkade, H. J., Weber, P. & Eggersdorfer, M. 2015. Increased Intake of Foods with High Nutrient Density Can Help to Break the Intergenerational Cycle of Malnutrition and Obesity. Nutrients, 7, 6016-37.
  18. Gernand, A. D., Schulze, K. J., Stewart, C. P., West, K. P., Jr. & Christian, P. 2016. Micronutrient deficiencies in pregnancy worldwide: health effects and prevention. Nat Rev Endocrinol, 12, 274-89.
  19. Bird, J. K., Murphy, R. A., Ciappio, E. D. & Mcburney, M. I. 2017. Risk of Deficiency in Multiple Concurrent Micronutrients in Children and Adults in the United States. Nutrients, 9.
  20. Beef, variety meats and by-products, liver, raw Nutrition Facts & Calories [Online]. SELFNutritionData: know what you eat. Available: http://nutritiondata.self.com/facts/beef-products/3468/2
  21. Enser, M., Hallett, K. G., Hewett, B., Fursey, G. A., Wood, J. D. & Harrington, G. 1998. The polyunsaturated fatty acid composition of beef and lamb liver. Meat Sci, 49, 321-7.
  22. Matschiner, J. T., Taggart, W. V. & Amelotti, J. M. 1967. The vitamin K content of beef liver. Detection of a new form of vitamin K. Biochemistry, 6, 1243-8.
  23. Dhiman, T. R., Nam, S. H. & Ure, A. L. 2005. Factors affecting conjugated linoleic acid content in milk and meat. Crit Rev Food Sci Nutr, 45, 463-82.
  24. Green, A. S. & Fascetti, A. J. 2016. Meeting the Vitamin A Requirement: The Efficacy and Importance of beta-Carotene in Animal Species. ScientificWorldJournal, 2016, 7393620.
  25. Harrison, E. H. 2012. Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids. Biochim Biophys Acta, 1821, 70-7.
  26. Reboul, E. 2013. Absorption of vitamin A and carotenoids by the enterocyte: focus on transport proteins. Nutrients, 5, 3563-81.
  27. Borel, P., Lietz, G., Goncalves, A., Szabo De Edelenyi, F., Lecompte, S., Curtis, P., Goumidi, L., Caslake, M. J., Miles, E. A., Packard, C., Calder, P. C., Mathers, J. C., Minihane, A. M., Tourniaire, F., Kesse-Guyot, E., Galan, P., Hercberg, S., Breidenassel, C., Gonzalez Gross, M., Moussa, M., Meirhaeghe, A. & Reboul, E. 2013. CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with plasma concentrations of these micronutrients in humans. J Nutr, 143, 448-56.
  28. Borel, P. & Desmarchelier, C. 2017. Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability. Nutrients, 9.
  29. Vitamin A: Fact Sheet for Health Professionals [Online]. National Institutes of Health: Office of Dietary Supplements. Available: https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/#en38 [Accessed].
  30. Vitamin A: Fact Sheet for Consumers [Online]. National Institutes of Health: Office of Dietary Supplements. Available: https://ods.od.nih.gov/factsheets/VitaminA-Consumer/ [Accessed].
  31. Blomhoff, H. 2004. Vitamin A regulates proliferation and apoptosis of human T- and B-cells. Biochemical Society Transactions, 32, 982-984.
  32. Parker, G. A. & Picut, C. A. 2005. Liver immunobiology. Toxicol Pathol, 33, 52-62.
  33. Freund, C. & Gotthardt, D. N. 2017. Vitamin A deficiency in chronic cholestatic liver disease: Is vitamin A therapy beneficial? Liver Int, 37, 1752-1758.
  34. Hobbs, R. P. & Bernstein, P. S. 2014. Nutrient Supplementation for Age-related Macular Degeneration, Cataract, and Dry Eye. J Ophthalmic Vis Res, 9, 487-93.
  35. Clagett-Dame, M. & Knutson, D. 2011. Vitamin A in reproduction and development. Nutrients, 3, 385-428.
  36. Borel, P. & Desmarchelier, C. 2017. Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability. Nutrients, 9.
  37. Zhang, X. K. 2002. Vitamin A and apoptosis in prostate cancer. Endocr Relat Cancer, 9, 87-102.
  38. Park, K. 2015. Role of micronutrients in skin health and function. Biomol Ther (Seoul), 23, 207-17.
  39. Gruber, R., Sugarman, J. L., Crumrine, D., Hupe, M., Mauro, T. M., Mauldin, E. A., Thyssen, J. P., Brandner, J. M., Hennies, H. C., Schmuth, M. & Elias, P. M. 2015. Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency. Am J Pathol, 185, 1012-21.
  40. Darwish, W. S., Ikenaka, Y., Morshdy, A. E., Eldesoky, K. I., Nakayama, S., Mizukawa, H. & Ishizuka, M. 2016. beta-carotene and retinol contents in the meat of herbivorous ungulates with a special reference to their public health importance. J Vet Med Sci, 78, 351-4.
  41. Darwish, W. S., Ikenaka, Y., Morshdy, A. E., Eldesoky, K. I., Nakayama, S., Mizukawa, H. & Ishizuka, M. 2016. beta-carotene and retinol contents in the meat of herbivorous ungulates with a special reference to their public health importance. J Vet Med Sci, 78, 351-4.
  42. Fiedor, J. & Burda, K. 2014. Potential role of carotenoids as antioxidants in human health and disease. Nutrients, 6, 466-88.
  43. Evans, J. A. & Johnson, E. J. 2010. The role of phytonutrients in skin health. Nutrients, 2, 903-28.
  44. Johnson, E. J. 2002. The role of carotenoids in human health. Nutr Clin Care, 5, 56-65.
  45. Di Pasquale, M. G. 2009. The essentials of essential fatty acids. J Diet Suppl, 6, 143-61.
  46. Simopoulos, A. P. 2002. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother, 56, 365-79.
  47. Simopoulos, A. P. 2016. An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity. Nutrients, 8, 128.
  48. Enser, M., Hallett, K. G., Hewett, B., Fursey, G. A., Wood, J. D. & Harrington, G. 1998. The polyunsaturated fatty acid composition of beef and lamb liver. Meat Sci, 49, 321-7.
  49. Horrocks, L. A. & Yeo, Y. K. 1999. Health benefits of docosahexaenoic acid (DHA). Pharmacol Res, 40, 211-25.
  50. Nagaraja, T. G. & Chengappa, M. M. 1998. Liver abscesses in feedlot cattle: a review. J Anim Sci, 76, 287-98.
  51. Nagaraja, T. G. & Lechtenberg, K. F. 2007. Liver abscesses in feedlot cattle. Vet Clin North Am Food Anim Pract, 23, 351-69, ix.
  52. Roberts, J. L. 1982. The prevalence and economic significance of liver disorders and contamination in grain-fed and grass-fed cattle. Aust Vet J, 59, 129-32.
  53. Nagaraja, T. G. & Chengappa, M. M. 1998. Liver abscesses in feedlot cattle: a review. J Anim Sci, 76, 287-98.
  54. Koréneková, B., Skalicka, M. & Naï, P. 2002. Concentration of some heavy metals in cattle reared in the vicinity of a metallurgic industry.
  55. French, K. E., Harvey, J. And Mccullagh, J.S.O. 2018. Targeted and Metabolic Profiling of Wild Grassland Plants identifies Antibiotic and Anthelmintic Compounds Targeting Pathogen Physiology, Metabolism and Reproduction. Scientific Reports, 8, 1-10.
  56. Pasture management in New Zealand [Online]. Progressive Forage. Available: https://www.progressiveforage.com/forage-production/producer-features/pasture-management-in-new-zealand [Accessed].
  57. Byelashov, O. A., Sinclair, A. J. & Kaur, G. 2015. Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid. Lipid Technol, 27, 79-82.
  58. Full Report (All Nutrients): 13325, Beef, variety meats and by-products, liver, raw. United States Department of Agriculture Agricultural Research Service, National Nutrient Database for Standard Reference.
  59. 1999. Animal Welfare Act 1999 [Online]. New Zealand: Parliamentary Counsel Office. Available: http://www.legislation.govt.nz/act/public/1999/0142/latest/DLM49664.html [Accessed].
  60. World Animal Protection [Online]. Available: https://www.worldanimalprotection.org/our-work/help-protect-animals-globally/review-animal-welfare-standards-around-world [Accessed].
  61. World Animal Protection – Rankings [Online]. Available: https://api.worldanimalprotection.org/ [Accessed].
  62. World Animal Protection [Online]. Available: https://www.worldanimalprotection.org/our-work/help-protect-animals-globally/review-animal-welfare-standards-around-world [Accessed].
  63. 1993. Biosecurity Act 1993 [Online]. New Zealand: Parliamentary Counsel Office. Available: http://www.legislation.govt.nz/act/public/1993/0095/164.0/DLM314623.html [Accessed].
  64. Law & Policy: Biosecurity [Online]. Ministry for Primary Industries. Available: https://www.mpi.govt.nz/law-and-policy/legal-overviews/biosecurity/ [Accessed].
  65. Biosecurity 2025 [Online]. Ministry for Primary Industries – New Zealand. Available: https://www.mpi.govt.nz/protection-and-response/biosecurity/biosecurity-2025/ [Accessed].
  66. How does the liver work? [Online]. PubMed Health. Available: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072577/ [Accessed].
  67. Rui, L. 2014. Energy metabolism in the liver. Compr Physiol, 4, 177-97.
  68. Werner, A., Kuipers, F., and Verkade, H.J. Fat Absorption and Lipid Metabolism in Cholestasis. Madame Curie Bioscience Database
  69. Blomhoff, H. 2004. Vitamin A regulates proliferation and apoptosis of human T- and B-cells. Biochemical Society Transactions, 32, 982-984.
  70. Parker, G. A. & Picut, C. A. 2005. Liver immunobiology. Toxicol Pathol, 33, 52-62.
  71. Grant, D. M. 1991. Detoxification pathways in the liver. J Inherit Metab Dis, 14, 421-30.
  72. Berg, J. M., Tymoczko, J.L., Stryer, L. 2002. Section 26.3The Complex Regulation of Cholesterol Biosynthesis Takes Place at Several Levels. Biochemistry. 5th edition. New York: W H Freeman.
  73. What is cholesterol and how does arteriosclerosis develop? [Online]. PubMed Health. Available: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072511/ [Accessed 2018].
  74. How does the liver work? [Online]. PubMed Health. Available: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072577/ [Accessed].
  75. Rui, L. 2014. Energy metabolism in the liver. Compr Physiol, 4, 177-97.
  76. How does the liver work? [Online]. PubMed Health. Available: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072577/ [Accessed].
  77. Michalopoulos, G. K. 2007. Liver regeneration. J Cell Physiol, 213, 286-300.
  78. Duncan, A. W., Dorrell, C. & Grompe, M. 2009. Stem cells and liver regeneration. Gastroenterology, 137, 466-81.
  79. Grant, D. M. 1991. Detoxification pathways in the liver. J Inherit Metab Dis, 14, 421-30.
  80. Albahrani, A. A. & Greaves, R. F. 2016. Fat-Soluble Vitamins: Clinical Indications and Current Challenges for Chromatographic Measurement. Clin Biochem Rev, 37, 27-47.
  81. Roberts, J. L. 1982. The prevalence and economic significance of liver disorders and contamination in grain-fed and grass-fed cattle. Aust Vet J, 59, 129-32.
  82. Sisson, S., Grossman, J. D. & Getty, R. 1975. Sisson and Grossman's The anatomy of the domestic animals.
  83. Premack, D. Hunter-Gatherer [Online]. University of Pennsylvania. Available: https://www.sas.upenn.edu/~premack/Essays/Entries/2009/5/15_Hunter-Gatherer.html [Accessed].
  84. Vitamin A: Fact Sheet for Health Professionals [Online]. National Institutes of Health: Office of Dietary Supplements. Available: https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/#en38 [Accessed].
  85. Razaitis, L. 2005. The Liver Files [Online]. The Weston A. Price Foundation. Available: https://www.westonaprice.org/health-topics/food-features/the-liver-files/ [Accessed].
  86. Albahrani, A. A. & Greaves, R. F. 2016. Fat-Soluble Vitamins: Clinical Indications and Current Challenges for Chromatographic Measurement. Clin Biochem Rev, 37, 27-47.
  87. Razaitis, L. 2005. The Liver Files [Online]. The Weston A. Price Foundation. Available: https://www.westonaprice.org/health-topics/food-features/the-liver-files/ [Accessed].
  88. Bendich, A. & Langseth, L. 1989. Safety of vitamin A. Am J Clin Nutr, 49, 358-71.
  89. Vitamin A: Fact Sheet for Health Professionals [Online]. National Institutes of Health: Office of Dietary Supplements. Available: https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/#en38 [Accessed].
  90. Rodahl, K. & Moore, T. 1943. The vitamin A content and toxicity of bear and seal liver. Biochem J, 37, 166-8.
  91. Albahrani, A. A. & Greaves, R. F. 2016. Fat-Soluble Vitamins: Clinical Indications and Current Challenges for Chromatographic Measurement. Clin Biochem Rev, 37, 27-47.
  92. Masterjohn, C. 2006. Vitamin A On Trial: Does Vitamin A Cause Osteoporosis? [Online]. The Weston A. Price Foundation. Available: https://www.westonaprice.org/health-topics/abcs-of-nutrition/vitamin-a-on-trial-does-vitamin-a-cause-osteoporosis/#newunderstand [Accessed 2018].
  93. Razaitis, L. 2005. The Liver Files [Online]. The Weston A. Price Foundation. Available: https://www.westonaprice.org/health-topics/food-features/the-liver-files/ [Accessed].
  94. Razaitis, L. 2005. The Liver Files [Online]. The Weston A. Price Foundation. Available: https://www.westonaprice.org/health-topics/food-features/the-liver-files/ [Accessed].
  95. 2016. Gerson Therapy (PDQ®) [Online]. PubMed Health. Available: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0032784/ [Accessed].
  96. Kumar, N., Boes, C. J. & Samuels, M. A. 2006. Liver therapy in anemia: a motion picture by William P. Murphy. Blood, 107, 4970.
  97. Price, W. A. 1939. Nutrition and physical degeneration; a comparison of primitive and modern diets and their effects, New York, London,, P.B. Hoeber.
  98. Deb-Choudhury, S., Haines, S., Harland, D., Clerens, S., Van Koten, C. & Dyer, J. 2014. Effect of cooking on meat proteins: mapping hydrothermal protein modification as a potential indicator of bioavailability. J Agric Food Chem, 62, 8187-96.